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10 mV is very little voltage to do anything with.  Our bq25504 energy harvester might be of interest.

Subba Reddy

0 mV   -- --------> 0 V
10 m V----------> 2.5 V
20 mV-----------> 5 V

Seems any non inverting amplifier with a gain of 250 will meet your requirement..

What is the load you need to drive?

Regards,

JayantD

Dear Jayanth,

Yes, i am going with non-inverting amplifier using LM 158 or LM 358. I am not going t odrive higher loads, not more than 20 m A.

Thanks for quick suggestion.

Regards,

Subba 

Hello Subba,

As Jayant suggested an operational amplifier set to a non-inverting gain of 250 V/V should accomplish what you need. If the operational amplifier is powered by a dual supply and is capable of delivering the 20 mA over a 0 to 5 V output range you should be set. However if you only have a single supply available, then you will need a rail-to rail output operational amplifier. A rail-to-rail output operational amplifier will swing just about to the supply rail voltage levels. The levels to which it swings will be a function of the output current required. An rail-to-rail output  MOS operational amplifier with high output current will put you closest to your required 0 to 5 V output range. Also, a single-supply amplifier for your application would require a common-mode voltage (CMV) input range that extends to 0 V. Fortunately, most single-supply operational amplifiers have an input range that extends to 0 V on the low end.

For example, the TLV4110 can deliver hundreds of milliamperes of output current; but if it is used at an level of 20 mA it will swing within a few tens-of-millivolts of 0 V on the low end and within a few of tens-of -millivolts of 5 V on the high end. Increasing the supply voltage to 5.25 V would allow the output to achieve a level of 5.0 V. The TLV4110 may be overkill for your application, but I use it to illustrate the point.

Best Regards, Thomas

PA - Linear Applications Engineering