AFE4300

Mike,

We have received your post and will get back to you shortly.

Mike,

Sorry for the delay. Electrodes are what we have used. Were you planning on using something other than electrodes? If so, what did you have in mind?

We have a few TI Designs that you might be interested in:

www.ti.com/.../tida-00008;tisearch=Search-EN-Everything

www.ti.com/.../TIDA-00009;tisearch=Search-EN-Everything

I did read about the 2 designs you refer to. My design is as follows, I think with a little help I can have a TI solution:

1. I need the BI Electrode to be used on the patient's upper Arm. In this case its a position on the arm to arm, as per example hand to hand. The data extracted would be used to get the Blood Pressure continuously.

2. The second case i need the BI Electrodes on the wrist, using the Chronos watch strap and the data extracted used to get the BP.
I want to use the measured radial Electrical Bio-Impedance (EBI). Need electrodes for this.

Research background;

Increasing mortality in developed countries, caused by cardiovascular disease, and mainly by
atherosclerosis and/or hypertension, is a major concern in modern medicine nowadays. Thereupon, the
situation requires developing of novel, non-invasive and reliable monitoring and diagnosing tools
capable to recognize a heart disease on its early progress stages.
Along with other parameters, the Central Aortic Pressure (CAP) and the Augmentation Index (AI)
have been indicated in several studies as important cardiovascular risk markers [1, 2]. It is well
known, that the CAP curve is formed from the sum of the direct aortic pressure wave, just pumped out
from the heart, and from the traveling wave reflected from peripheral arteries. A quickly arrived
reflected wave will produce an increase in the CAP, and significant rise of which can be recognized as
a risk marker. Thus estimating the contribution of a reflected wave to the CAP gives important
information about condition of arteries and patient health risk.
Non-invasive estimation of the AI and the CAP is usually done by a well-known applanation
tonometry, when a peripheral blood pressure is measured on a radial artery and then calibrated by the
pressure values obtained using the brachial cuff. After that both, the CAP and the AI values, are
estimated from the measured radial pressure and generalized transfer function [3 - 6].

We are replacing the old way of the "Applanation Tonometry" with EBI. I think TI has what I want just need your help fitting the pieces together.

Update

The GlobalhealthUSA continuous blood pressure monitor doesn’t rely on a typical pressure cuff, but rather on a patch that has electrodes that sense the changing impedance of tissue around a vessel, the data from the electrode is converted it into a BP reading. Measuring other characteristics in electrical signal can also identify vascular stiffness and pulse velocity.

 

The GlobalhealthUSA smart patch, which the doctor or nurse places on the patient’s upper arm. From there, the unit monitors the patient’s blood pressure over 24 hours and stores the data for subsequent analysis via an enclosed piece of software. The result is comprehensive data about the patient’s blood pressure over 24 hours and thus an optimal basis for making the correct diagnosis. We plan to obtain FDA approval for the device.

Mike,

This is very interesting.
What is it that I can do to help you?

send this doc0422.docxCan you answer the questions in attached document. Thanks for your help.

Can you answer these questions AFE4300?

 

Use of TI Tetra-polar Single (SF-BIA) and Multi-frequency (MF-BIA) BIA will be used to measure the bio-impedance. Here is TI picture of the Tetra-Polar electrode on a chest. I am doing the same on the wrist.

Question: Do I have to build my own Tetra=Polar electrode as in Fig-2? If yes

                 Do you have a sample schematic you can send me?

                 The documentation claims that there are existing algorithms for body measurements,

                  Can I download them?

 

Texas Instruments Bio-patch solutions

 

Can we use the tetra-polar sensor above in Fig-1 Bio patch together with the AFE 4300 or is the bio patch for none bio Impedance sensors?

What then is the difference between the AFE4300