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TPA3251: question about GND Pin

Part Number: TPA3251

the left side GND pin 12,13 from 12V power source, name the GND to P_GND

the right side GND pin 34,41,42 from 35V power source, name the GND to A_GND

may be has little volts( usually<0.5v, name V1) between P_GND an A_GND when 35V Power source has high loading. 

my question is

A: the little V1 will damage the chip?

B: make chip unstable working ?

C: make extra noise?

D: all GND pin is connected in chip internal?

E: will be better sound qulity and better Channel Separation?

any one known it?

thanks!