ADS131A04: Differential Input Signal with DC Offset from a Single Supply ADC Output Codes

Part Number: ADS131A04

We are utilizing the ADC as a single 3.3V device with an external REFEXT of 3.0V supplied by a REF1930. The analog signals are offset to 1.5V also from the REF1930. We are using multiple device chaining with the first device configured as asynchronous interrupt mode and the remaining devices configured as synchronous slave mode. All devices are configured for 32 bit SPI word transfers and Hamming code is turned off. According to the datasheet Data Words in Table 10. 24-Bit Ideal Output Code versus Input Signal the output codes are output in 2's complement format. What is the proper method to compensate for the 2's complement? Can this be turned off?

Thank you,