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DNA-chip litography using DMD (digital micromirror device)

Dmitry Andreyev
Prodigy 20 points
Other Parts Discussed in Thread: DLPLCR4500EVM, DLP6500FYE

I'm looking for help in building a simple DMD-based device for DNA chip lithography, e.g. like the one described here: https://www.nature.com/nbt/journal/v17/n10/full/nbt1099_974.html

Any advice or discussion regarding suitable device, it's controlling and interface would be highly appreciated.

  • 0
    TI__Mastermind 43135 points

    Hello Dmitry,

    Welcome to the DLP section of the TI-E2E community.

    This will depend on how much resolution you need. A very good starting candidate would be the DLPLCR4500EVM. This unit has a reasonable cost and a fairly good GUI interface.

    If you need more resolution and flexibility the DLPLCR6500EVM is another option, but it does not come with optics.

    If you need lower cost to start with as a proof of concept the DLPLIGHTCRAFTER (uses the DLP3000 DMD) is a good candidate.


    Fizix

  • 0 in reply to Fizix
    Prodigy 20 points

    Hello Fizix, thanks for your suggestions. I have thought about DLP6500FYE with controller, but I did not realized there is assemblies with optics already installed, it is very interesting.

    However, as far as I understand, the DLPLCR4500EVM uses RGB light and I probably will have to substitute it for 365nm UV (well, I can go with 400 and even above, but it will complicate chemistry). So is this "light engine" easily modifiable? Is its optics near UV-transparent? What shortest wavelength it can provide with default LEDs? And what size of pixels it provides without additional optics? 

    I'm thinking about installing the device to top of inverted microscope illumination optics (instead of a lamp, with an extra lens), and use a UV laser (or, if speckles will be a problem - UV LED with collimating optics). Is there any assembled or half-assembled solutions, or it is better to go to Thor Labs and assemble everything from a scratch?

    I also wander if there is any ready-to-use software for these mirrors or I will have to write my own? Something very simple, allowing to switch pre-set mirror states every minute or so would be sufficient. Capability to take or generate external synchronization signal would be ideal. Any suggestions?   

    Dmitry