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Can I use DIrectI/O and message at the same time when develop under c6455 environment?

Hello, I'm  using  srio under c6455, I found that csl only support direct I/O,while MQT only support message, if I want use both of them ,how can I initialize the srio,could some one give me some advice, furthermore, I don't have any Idea when to use direct io and when to use message,