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TUSB2077A port usage

Hi ,

I am designing a new board using TUS2077A and connecting to FT232RL for serial hub.
My questions

1.Can I use all the 7 Ports for Ft232RL.

2. I have made a prototype with this one 5 ports. 4 Ft232RL and one PIC micro controller. But in my board two FT232RL ports are detecting and one PIC also detecting the remaining 2 ports are not detecting, any reasons?

Using Self power:

Anoop