We have a issue when using we are interfacing TXB0104 and SN75451B. SN75451B is used for TX driver for Fibre Optic Transmitter HFBR-1412PZ and operates at 5V, TXB0104 is used to convert UART 3.3V level to 5V level Issue: When We provide UART signals (5V) TTL level directly to SN75451B and to FO converter, it works But when we provide same UART signals (@ 5V) which are level converted from 3.3V through TXB0104, FO is not working, Schematics for TXB0104 and FO with SN75451B are attached.