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TPS2547: TPS2547 wakeup from S0 to S3

Part Number: TPS2547

Dear all,

we have application and set the system from S0 to S3, when connecting the mouse to the port, it can wake up from S3 to S0.

But when firstly connect Hub to the port, and then connect the mouse to the Hub, it can not wake up from S3 to S0, could you please advice what is the possible reason?

Thanks.