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TMDS181: Asking for TMDS181 setting

Part Number: TMDS181

Hi Team,
Customer uses TMDS181, and they try to set 0Bh bit 1 to 0, however, it will become 0.
Would you please provide your comment for this?

if set 0Ah bit 5 to "1",  will that impact 0Dh's value? 

BR,SHH