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SN65LVPE512: Are they possible to use both transmission side

Part Number: SN65LVPE512
Other Parts Discussed in Thread: TUSB522P

Dear Specialists,

My customer is considering SN65LVPE512 and has an inquiry.

Could you please advise?

---inquiry

The datasheet describes typical application, the device is set host side

Are they possible to use the device  both transmission side ?
I’d like to boost not only host side, but also device side. 
 
Could you please see attached file.
 
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I appreciate your great help and cooperation in advance.
 
Best regards,
Shinichi