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TXB0108: Power calculation

Part Number: TXB0108

1) which current parameter to be used for power calculation of this component (or any comonent) in circuit.
2) current rating at various voltage levels (page 6 of datasheet)
3) contineous current through Vcca, Vccb or GND, and how it is diffrent from same specification mentioned in SN74AVC16T245. (page 5 of datasheet)