Other Parts Discussed in Thread: SN74LVC125A
SN74AVC4T245 is being used to translate between 1.8V and 3.3V. VccA = 1.8V, VccB = 3.3V. Device is set to translate from B to A on all ports. See attached schematic.
Noticed that VccB current increases by about 45 mA when VccA is turned off. There are other devices on the VccB rail, but seems unlikely any of these are source of current increase.
When VccA is off, VccA voltage falls to about 0.2V. Is this low enough to place device into Vcc isolation or Ioff mode? All I/Os on B side are pulled up to VccB (even pin 14 which does not show pull up on schematic).