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How to protect clock signals from hot Plugging

Other Parts Discussed in Thread: SN74CBT6845C

Hi ,

    I‘m evaluating a frame switch,it contains 2 switch board and 8 line card;all switch board and line card should support hot plugging;So how to protect clock signals and other Single-ended signals from hot Plugging?

   I'm not familiar with the standard of this kind of application scenes if there has;Although I have met the use of SN74CBTLV3245 for this kind of application,but i am not very  if it is suitable;Pls help to provide correct IC to satisfy this application,Thanks!