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TXB0104: VCCA operating current estimation

Part Number: TXB0104

Hi,

  I'd like to know how I estimate the operating current on both of VCCA and VCCB rail. From data sheet, 5uA is max. number, at Io =0. is 5uA real operating current?  or without signal transition? 

  on real signal operation board, how do I estimate the real operating current?