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+/- 400V Variable output controller

Hello all,

I am looking for some direction in creating a variable +/- 400V @ 10uA max output controller. Currently I have a flyback solution designed that can do it, but there are issues with the feed back voltage resolution and the way the microcontroller is managing the output voltage. It would be nice if I can find a controller that is able to handle the regulation for me with <1mV of output ripple for the purpose of this product. 

Here are the specs: 

5V input

Variable +/- 400V output

output voltage ripple: < 1mV

output supply current: <=12uA

Thanks all!