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TLC59581: New design - latest tools?

Part Number: TLC59581

We are starting a design for daisy-chained LED RGB displays in various resolutionss. 

Each module will have 64x64 RGB LEB, 80x80, etc.

It seem that using an integrated design would be best to limit points of failure (existing Chinese design use small 16 channel drivers).

What is the best path using the latest TI offerings? We saw reference designs for TI5958.

If we made module based on TLC5958x how do you drive them? Are any receiving/sending card compatible to send HDMI signals to the panel?

With thanks, David