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INA210: Low side Current sensiing at very high voltage

Part Number: INA210
Other Parts Discussed in Thread: INA181

I am designing a current sensing application on a solar PV line. The line voltage will be around 1500V DC. Since we are planning to measure the current on the low side

1. Can the current sense amplifier be connected to the shunt directly?

2. Should I consider any other additional design constraints?