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INA333: ground connecting issue with differential amplifiers

Part Number: INA333


Tool/software:

Hello, I would like to ask about the possibility of using the INA333 for measuring current in a 4-20 mA loop, and the related issue of connecting the grounds of the devices. Do I need to connect the grounds, or is the circuit capable of measuring the voltage across a resistor without linking the grounds of both devices? Thank you in advance for your help.