The TAS52xx GUI says it's "Off", but settings to BQ3 (and BQ1) also affect the other channel. Likewise settings to BQ4 (and BQ2) affect (actually replace) the settings of BQ3 (and BQ1).
When I click "Apply and Draw" in the biquad GUI, the settings to BQ3 are applied to the channel supposedly being controlled by BQ4, and vice versa. Whichever one I click last replaces the settings of the other.
Example: BQ3#1 set for HP BW2 2000Hz. Clicking "apply and draw" puts the filter on both channels. Then BQ4#1 is set for LP BW2 2000Hz. Clicking "apply and draw" affects both channels, and replaces the previous settings.