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AFE4404: the waveform drift issue

Part Number: AFE4404

Dear TI partner,

My customer select AFE4404 to design blood oxygen measurement product.now they had design test board by themselves.

now they catch the ADC output data and make simulation waveform,find the waveform drift very seriously. can you help analysis the reason?such as noise or layout or other reason?

below is the schematic and software and test waveform.for your reference.

part schematic