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ADS114S08: Question on using Vref for other application

Part Number: ADS114S08

Dear TI Expert,

  We have an application of detecting 4~20mA signal.  So far, we've designed to use a resistor of high precision and a non-inverting opamp to amplify the signal. which is then fed into ADS114S08's analog input.  Because our application has high priority on low current consumption, we wonder if we want to use internal 2.5V reference (REFOUT) for opamp's bias voltage (since REFOUT can be configured power down when ADC is in power down mode), is that ok? Or should this 2.5V reference be left alone, never be used for other purpose?  Or it can be used, only some care needs to be taken care of?

Hope someone can shed some light on this.

Yuanchen Zhu