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ADS1198: How often GPIO is latched to register in ADS1198?

Part Number: ADS1198

We have configured ADS1198 for GPIO1 and  follwing SPS

Register(1)=0x6,  //125 SPS

Register(20)=0x01,//GPIO1

 and GOIO1 pin is being driven by another chip asynchronous to ADS. From what I understand GPIO1 is latched into GPIO register for next output data frame on SPI bus. 

Question is if GPIO1 is being sampled at the ADS sampling rate? Or register values reflects immediate changes on GPIO?