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ADS1298 EEG Pre-Amp interactions

Other Parts Discussed in Thread: ADS1298, ADS1278, INA114, INA131, INA333, INA126

 

I’m currently evaluating the ADS1298 for an update and extension of a multi-modality data acquisition system.  Modalities include eeg, emg, heart rate, GSR and temperature, but the main focus is EEG.

I want to know about sampling rates as well as several issues related to using the ADS1298 with an in-amp pre-amp.

Regarding sampling rates, is there a way I can get continuous mode power of two sampling rates (255 SPS, 512 SPS, 1024 SPS etc) perhaps by changing Fclk?

If not, what are the disadvantages to using single-shot mode?  Is there a better explanation of the increased issues of aliasing effects alluded to on page 36?

 

Regarding using an in-amp pre-amp, from reading the discussion board I understand that the noise floor and amplification of the ADS1298 is insufficient for eeg taken on the scalp without the addition of a low-noise in-amp pre-amp. 

I would like to know how to design a system that includes an RLD, Lead-off detection and EMI filtering while using a pre-amp.  It appears there are some trade offs between relying on circuits that are built-in to the ADS1298 for  RLD, Loff, and RFI filter and using off-chip circuits that may be better incorporated into the pre-amps.

Specifically:

RLD

In a typical in-amp based design the input from the RLD circuit is taken from the middle of the gain setting resistor in the in-amp.  Regarding accuracy .1 % resistors are cheap and available and a third resistor in parallel helps to equalize the currents.  

The input for RLD circuitry on the ADS1298 is taken from the gain setting resistors in the PGA.   A big advantage of using the built in RLD circuitry is the ability to choose which channels are used to derive the RLD signal, i.e. the RLD source signal may be limited to appropriate channels in use.  Whereas, an RLD derived from the sum of several in-amps might include an unused channel without adding addition of circuitry and control lines to turn an unused input off.

Question: In an EEG system which source will provide a higher quality RLD signal input one derived from the on-chip RLD or one derived from the middle of the gain setting resistor of the in-amp?

 

Lead-Off  Detection

Can I use the on-chip lead-off circuitry to generate an electrode impedance measurement?

Please advise on the options for using the lead-off detection when using pre-amp.

Would I use the AC or DC measurement?

With AC measurement is the signal typically filtered in hardware or software?

Is it rectified?

Do you have a source code snippet for this procedure in software or a circuit diagram for doing it in hardware?

 

EMI Filter.

In an eeg/ekg design EMI/RFI circuitry is typically placed before the in-Amp to avoid offset and saturation caused by rectification of high frequency signals beyond the bandwidth of the  in-amp.  This issue will likely worsen in the future as wireless devices increase.

In an ADS1298 based EEG with an in-amp, the built-in  EMI section of the ADS1298 would follow the in-amp.  Seems that the in-amp should have EMI circuitry preceding it.

Will the EMI circuitry in ADS1298 cause any interactions with the pre-amp?

Would it be better to use an ADS1278?

  • **TI EDIT February 20th 2019; FOR GENERAL ADS129x ASSISTANCE, PLEASE SEE NEW BIOPOTENTIAL FAQ LOCATED HERE**

    Hi Jon,

    I'll contact you off line to try and get some of these questions answered for you.

  • JonP,

    Please let me introduce myself.  My name is Robert Burnham.  I am responsible for Strategic Marketing of our Biopotential Analog Front End devices.

    I have several options for EEG applications that will help you with your system design.

    I look forward to hearing from you soon.

     

    Regards,          

    Robert J. Burnham

  • Hi Tom,

    Can you answer these questions in this forum, please

  • Hi Artem,

    The original post had a fair amount of detailed questions relating to ECG and EEG. Is there any specific part of the post that you were interested in. I will answer a few of the questions below in red.

    Some low noise INA pre-amps that you could use are the INA114/115, INA126, INA131, and INA333. You can take a look at those to see if they work.

    Regarding sampling rates, is there a way I can get continuous mode power of two sampling rates (255 SPS, 512 SPS, 1024 SPS etc) perhaps by changing Fclk?

    In a typical delta sigma converter, changing the fclk will scale the data rate. The ADS1298 external master clock frequency is limited from 1.94MHz to 2.25MHz to keep the part within spec so you are not going to have enough room to change the master clock to change the data rate from 255 to 512 to 1024 using the Fclk. Best way to do something like this is use the internal settings to cycle through data rates. You will have to stop the converter as the data rates are changed so it would not be continuously. 

    If not, what are the disadvantages to using single-shot mode?  Is there a better explanation of the increased issues of aliasing effects alluded to on page 36?

     ECG and EEG signals rely on a series of data points in order to reconstruct the signal in the digital domain. Single shot mode will only take one conversion and stop waiting for another convert trigger.

    Question: In an EEG system which source will provide a higher quality RLD signal input one derived from the on-chip RLD or one derived from the middle of the gain setting resistor of the in-amp?

    I would recommend reading the application note below on improving CMR using the RLD. The best route would be to use a RLD feedback loop from the input - 

    http://www.ti.com/lit/an/sbaa188/sbaa188.pdf  

    Lead-Off  Detection

    Can I use the on-chip lead-off circuitry to generate an electrode impedance measurement?

    With AC lead-off, there is a way to monitor electrode impedance measurement. However, a large part of it would depend on the composition of the electrode itself.

    Please advise on the options for using the lead-off detection when using pre-amp.

    Would I use the AC or DC measurement?

    Lead-off would have to be done discretely if a preamp is used. Lead-off relies on monitoring the electrodes when an excitation signal is applied. The preamp will isolate the lead-off excitation signal from the electrodes. A discrete DC solution using current sources and external comparators may be an option.

    With AC measurement is the signal typically filtered in hardware or software?

    The signal would have to be filtered in the post processing stage in the uC, DSP, FPGA.

    Is it rectified?

    The AC lead-off signal is not removed if that is what you are asking. You will need to develop bandpass filters in the post processing stage to distinguish between the ECG signal and AC excitation signal.

    Do you have a source code snippet for this procedure in software or a circuit diagram for doing it in hardware?

     You can look in the data sheet to see how lead-off is implemented internally.

    EMI Filter.

    In an eeg/ekg design EMI/RFI circuitry is typically placed before the in-Amp to avoid offset and saturation caused by rectification of high frequency signals beyond the bandwidth of the  in-amp.  This issue will likely worsen in the future as wireless devices increase.

    In an ADS1298 based EEG with an in-amp, the built-in  EMI section of the ADS1298 would follow the in-amp.  Seems that the in-amp should have EMI circuitry preceding it.

    Will the EMI circuitry in ADS1298 cause any interactions with the pre-amp?

    The internal EMI filter is a RC, 5K/10pF (I think), filter. It is before the internal PGA amplifier.

    Regards,

    Tony Calabria

  • Hi Tony,

    Thanks a lot for your detalied reply. It seems that at present the best way for EEG front-end is the discret solution.

    Regards,

    Artem Vdovjuk