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ADS1258 driving PGA281

Other Parts Discussed in Thread: PGA281, ADS1258, THS4521, TLV1704

Hello,

I'd like to use the ADS1258 and place a PGA281 between the MUX and the converter inputs. This way I can have the (great!) autoscan feature with a common gain for all channels (which I'm ok with). 

So I have two questions:

Do I need to add a low-pass filter after the PGA and use THS4521 to buffer the signal just before the A/D ? Or a low-pass filter directly fed into the A/D is ok ?

Also, I'd like to use the PGA GPIO to drive the PGA gain. Problem is, on the ADS, the DGND is at 0V, DVDD is 3.3V and on the PGA, VSON is at -2.5V and DVDD is at 2.5V. So I need to make some kind of level shifting. Is there any easy way to do this ?

Thanks in advance !

Norman