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ADS8902B: What is the minimum sensitive voltage input of the part ADS8902B

Part Number: ADS8902B

By referring the datasheet of ADS8902B, it says Vref Input Range: 2.5-V to 5-V

For the minimum Vref 2.5V, it is understood that the input analog voltage of 2.5V will give the output as FFFFF Hex. so that the LSB is (2.5/220 ) = 2.384μV. So that I give this much smaller voltage to input, does this part will sense, convert and give the answer 00001H? or is there any offset/tolerance or limitations will affect the output? What is the the minimum allowable analog input which is sensible and the conversion get start?