The part states for the +/-Vref input range that the common mode voltage should be Vref/2 while for +/-2xVREF the CMV is Vref. For a 5V analog rail the Vref VCM makes sense with +/-2xVref input range because Vref/2 VCM at 1.25V would clip things for 10Vpp inputs, but I mistakenly found that for the +/-Vref input range (5Vpp) using 2.5V for Vref that having the VCM at 2.5V also looks to work perfectly fine. It would seem that no matter what the input range is having VCM at 2.5V for a 5V analog input rail would optimize headroom. Is there anything reliabilty or performance wise that is really preventing me from just using 2.5V VCM for the +/-Vref input range?