Guna
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Hi Guna,
Thank you for providing the pdf.
After review I have a couple of suggestions:
1) The VCAP1 & VCAP3 capacitor connections should be changed. This can be seen in figure 106 of the data sheet.
2) 100k for R35 may be larger than intended - but it should be fine. Reducing to 10k should also be acceptable.
3) The ECG front end filter poles are at 48kHz and 723kHz. Is such a wide bandwidth needed?
4) Have you considered adding a differential cap of 220pF (10*Ccm) close to the inputs?