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PCA9306-Q1: PCA9306TDCURQ1

Part Number: PCA9306-Q1
Other Parts Discussed in Thread: PCA9306

How to explain this sentence as follows, if I2C from SOC(1.8V) to IC(3.3V), SOC I2C is open drain, but IC's I2C is LVTTL, not open drain, how to confirm the direction? If use PCA9306 is not fine?

"However, if either output is totem-pole, data must be unidirectional or the outputs must be 3-stateable and be controlled by some direction-control mechanism to prevent high-to-low contentions in either direction."