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TUSB8041: Series connection to achieve 16Ch USB3.0 Hub

Part Number: TUSB8041


I'm designing USB3.0 - 16CH - HUB for test automation purposes

In Market I found TUSB8041 - 4 CH USB 3.0 supporting IC. I'm planning to have 4xTUSB8041 to archive 16CH USB3.0 Hub.

Below is my high level block diagram. will TUSB8041 work in this configuration. 

If not, can you please guide me how to achieve 16CH USB Hub.