Other Parts Discussed in Thread: TPD4E02B04
if use two device of TPD4E02B04-Q1 on the PCIe path, Is there any signal integrity problem we might met?
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Be careful with trace capacitance - depending on what your speed of the PCIe bus you could have signal integrity issues due to the TPD4E02B04 capacitance. The best way to look at this is to look at the insertion loss plot of the device. Without knowing the speed of your bus specifically, I cannot tell exactly however.
It looks like PCIe gen 3 does 1 GBPS per line, so the bandwidth of the third harmonic is approximately 1.5Ghz. At 1.5Ghz the insertion loss for the TPD4E02B04 from the datasheet plot is approximately ~.25dB, so with two devices you can expect to see about .5dB loss at the third harmonic of your frequency.