Hello Everyone,
I have attached an image of my setup. 
I am able to send the address of the TCA9548A from my microcontroller and enable the 0 channel. I have scoped and verified that works just fine. I then try to send data after that to my amplifier in I2C and there is no data on the other side of the mux. I connected a bus pirate directly on the other side of the MUX and was able to read the registers and everything just fine. For some reason, even though I am able to set the channel and talk to each device seperately, the mux will not send the data through. Maybe a resistor issue? I don't think so since the scope shows a straight 5V signal and indicates nothing is being pulled down. Maybe the VCC needs to be set to 3.3V? I might see that as an option but its odd that it is able to talk to the micro and really the VCC is being used as a translator and needs to support the 5V bus.
