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DS160PR412: DS160PR412 and DS160PR421 application different from standard

Part Number: DS160PR412
Other Parts Discussed in Thread: DS160PR421

Hi Team,

My customer would like to use DS160PR412/421 in their system. We have some questions as below. Could you provide your professional comments? Thank you.

1. Could we exchange P and N signal? Normally, Tx_P→Rx_P will be used. But customer would like to exchange to Tx_P→Rx_N  because of layout. Is it okay?

2. Could we reverse pin number order? Normally, Tx3_P→Rx3_P will be used. But customer would like to change to Tx3_P→Rx0_P because of layout. Is it okay?

3. Could we place DS160PR412 and DS160PR421 at same location, one is at top side and another one is at bottom side. Has it any concern?

Best regards,