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ISOW7821: Can the device regulate 3.3V to 5V?

Part Number: ISOW7821
Other Parts Discussed in Thread: ISOW7841A-Q1

Hello,

I can see that the datasheet clearly shows 3 use cases for VCC to VISO which are

  1. 5V to 5V
  2. 5V to 3.3V
  3. 3.3V to 3.3V

Will 3.3V to 5V not work at all? Could it work for a much lower output current? 

Thanks,

John