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ISO1410: Should the isolated grounds be connected together?

Part Number: ISO1410
Other Parts Discussed in Thread: THVD1450

Hi Team,

There are two different PCB board, each of the board has ISO1410B with isolated power. If the two ISO1410B are connected, A/B lines should be connected together, may I know should the isolated ground GND2 be connected together? I think it's not necessary, could you please help confirm? Thanks!

If one ISO1410B and one RS485 such as THVD1450 are used, should the GND2 of ISO1410B and GND of THVD1450 be connected?

Best Regards!

Hao