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SN74AXC8T245: replace SN74AXC8T245 with SN74LXC8T245

Part Number: SN74AXC8T245
Other Parts Discussed in Thread: SN74LXC8T245, , TXV0108, TXV0106, TXU0304, TXU0104, TXU0204

Tool/software:

Can i replace SN74AXC8T245 with SN74LXC8T245.

The last one seems better / faster. I need to shift mostly up from 1V8 to 3v3 and occasionally 5V.

The SN74AXC8T245 is currently used on a RMII bus, can the SN74LXC8T245 be used in this application too? regarding data rate it should be better. Is there a reason there are no RMII applications with this chip?

Same questions for RGMII 

Best regards,

Robert