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SN74AVC4T245-Q1: If I try to power down both power rails, how does this device fail?

John Louie
Prodigy 80 points
Part Number: SN74AVC4T245-Q1

Hello,

I have an instance where I shut down both VCC of this device, but I still have signals feeding in from a microcontroller, will I run into a back-feeding issue?

Thank you,

John Louie