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SN74AVC4T245: can't set SN74AVC4T245PWR to sleep mode and get 5uA

Part Number: SN74AVC4T245
Other Parts Discussed in Thread: SN74AXC4T245,

Hello TI support

Please help me to understand what is wrong in my schema/ connection.
I can't set SN74AVC4T245PWR to sleep mode and get 5uA

The left side of 1V8 come from, stand alone LDO the managed by LTE modem, once LTE modem ready to work it turn ON LDO 1V8.
The right side of 3V3 connected always. always under 3V3 power.

CS managed from CPU, on sleep mode Q2 is not connected and pin 15 and 14 tying to 3V3.

My device should work from buttery and power consummation is my issues.
When a SN74AVC4T245PWR is set as I wrote above i got total current consummation 1.2mA.
when i remove two units U5 and U4 from board the current reduced to 0.2mA

I set a pins of UARTs that going to controller as Analog inputs.
LTE modem U1 under shut down mode

What i am doing wrong? please advise.
I need insert two devices U5 and U4 to sleep mode
Thank you