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SN74AXC4T245: Confirmation needed for using SN74AXC4T245 for 2 pairs of UART and take SN74AVC4T245 as alternative

Part Number: SN74AXC4T245
Other Parts Discussed in Thread: SN74AVC4T245

Hi there,

Currently I'm studying multiple pairs of 3.3V to 1.8V UART level shift option for my design, so far my plan is use SN74AXC4T245 for each two pairs of UART, and take SN74AVC4T245 as the alternative part in my BOM since both these two specification should meet my design request.

But since I don't have the experience of using these two product, can anyone help reviewing this kind of design is feasible? Especially of taking the SN74AXC4T245 and SN74AVC4T245 as the alternative for each other.

Here's the block diagram, please kindly help review it if there's anything should be modified, thanks in advance!

Tim