Recently I asked TI about using the DRV8106 as a bidirectional cut-off switch pre-driver. I would also like to know if the DRV8106 can be used as a unidirectional high-side pre-driver for a channel that supports 100% high side on-time with no low side output activation. Something like the picture above. I understand this may not be resolved until you get the board and test the other, more complex configuration but I am interested in this one too.