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TPS6521845: TPS6521845 substitute to TPS65218d0

Part Number: TPS6521845
Other Parts Discussed in Thread: TPS65218D0, , AM4376

I have a design based with TPS65218D0 that works perfectly. 

For availability reasons I had to mount the TPS6521845 instead of the TAPS218D0.

The tps6521845 activates for 20s and then turns off. 

Please Any ideas?

Attached hardware image to check POWER_EN connection.

If I try to externally program the system with tps6521845 the registers are not updated. 

Please Any ideas?

Note: CPU AM4376