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LM27761: What is wrong with my circuit?

Part Number: LM27761

Hi guys, image of circuit attached. 

C50,53 = 4.7uF 

C55 = 1uF

R2 = 105K

R3 = 100K

C46 = 2.2uF

As per equation 5; -1.22 * (105K + 100K)/100K = -2.5

Why wont this circuit output anything? I have tried 3 different chips all new. I can only think that using resistor values as high as 100 and 105k are the problem but regardless i didnt think that should be the issue as R2 should not be below 50K either as stated by datasheet. Power goes in, i can see 5V is input but the output is not working. 

Is it perhaps because i have left the EN floating? Couldnt find mention of leaving it floating in the datasheet? 

Thanks for any help :)