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TPS65132: spec check

Part Number: TPS65132


1.The TPS65132SYFFR chip uses a fixed output of ±5.4V and does not require I2C to adjust the voltage. Do the two I2C signal lines need to be processed? Can be left floating

2.D2 pin (AGND) is in the middle, with a 4mil line width, and a 4mil spacing between adjacent lines. Is it feasible?