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Power Dissipation Estimate for TPS54240-Q1

Other Parts Discussed in Thread: TPS54240-Q1


I'm trying to understand the equations which are given in the data sheet to estimate the power dissipation of TPS54240-Q1:

What is the physical meaning of the used constants "0.25x10^-9, 3x10^-9, 116x10^-6" ?

Thanks in advance.