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bq2060 - Cell 4 calibration factor

For many years this value would measure <10 but now after the redesign of the PCBA it now measures up to 50 while all other cell calibration factors remain under 5.  The measurements of the individual cells and the battery pack voltage are as expected.

Does seeing such a difference in the calibration offset indicate an issue with the circuit?

What do you believe the range of acceptable values should be?