I configured the circuit with TPS54560 .
50V battery input -----> 5V ,5A output
but , the VIN part burst at the moment of connection.
It works fine with 20V and 30V input...
It shows 4.5v to 60v input on datasheet.
What's wrong?
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It looks like you dont have a damping/electrolytic capacitor. On power up, with long leads (inductance in input path), you can experience rininging. This ringing can be large and cause the absmax of the device to be violated.
Can you monitor the input voltage when you power on the device at the VIN (input capacitor) of the device?
Can you slowly ramp up the input voltage to 50V with a DC supply and observe performance?