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BQ40Z50-R2: Unable to get circuit power up or communicate...Need Schematic Review please !!

Part Number: BQ40Z50-R2
Other Parts Discussed in Thread: BQ40Z50, EV2400, BQSTUDIO

Hi

  We have designed a circuit around TI reference design of bq40z50. We have be40z50evm and ev2400. We can communicate with the evm and ev2400 without any issues however I cannot get any of my board powered up from our own circuit. This is my 2nd prototype batch after I made some changes to first batch which again I could not get to communicate.

Can you guys please take a moment and look at my schematic and try to help me out. It is really discouraging at moment and about to give up on this. 

Kindly also let me know if pin 16 PRES can be left floating ??

Also any tips on debugging the circuit. I am not getting any voltage on pack output and can't communicate with bqstudio.

Thanks very much and looking forward to hear back.