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BQ25730: BQ25730 about I2C

Part Number: BQ25730
Other Parts Discussed in Thread: , BQ24610, BQ25713
Hi.
My company is going to use BQ25730 this time.

The bq25730 is controlled by i2c, but our product cpu works only by pressing the power button.
So, can the bq25730 be operated when the charger is plugged in while the I2C is not working?