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TPS65680: what the function of 0xFF bit[1]

Part Number: TPS65680

Hi, All

As the attachment picture. When we set 0xFF bit[1] = 1, what is the different with 0xFF bit[1] = 0?

As the description of 0xFF bit[1], this has a different when we execute reload.

What is the reload, load data from OTP to register? another question which register belong to "user setting"?