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UCD90160: Device inoperable/in reset until connect to Fusion GUI

Part Number: UCD90160

I have a UCD90160 on the circuit card I've been developing on.  I have done many writes and stores on this device and today it stopped sequencing without the Fusion GUI running.  If I disconnect the USB adapter on power-on, my power rails do not enable.  Once I open the Fusion GUI , as soon as the Fusion Digital Power Design scans for USB device, the UCD90160 finally starts a power-on sequence.

Have I somehow corrupted the internal firmware?  I have run an erase and reprogram on the device, but it still behaves the same